1,266 research outputs found
Possible deviations in the determination of bulk solid characteristics, caused by the loading mechanism of the Jenike Shear cell
In the literature ample attention is given to the assumptions on which the interpretation of shear-test results from a Jenike shear tester are based. Very little is said, however, about the influence on the test data of the construction of the apparatus itself. In the work described here, the authors have investigated the influence of the loading mechanism on the results. The original Jenike-type tester and a slightly modified one are considered.\ud
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From the equilibrium conditions, the real normal and shear stresses on the assumed shear plane were derived, which were found to deviate from the external applied stresses. The deviations in the primary results and derived data were quantified by introducing correction factors, the boundary values of which could be calculated.\ud
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Experiments with three different bulk materials were performed to measure the relevant quantities and to verify the assumptions used in theoretical analysis. Furthermore, the real normal stress on the shear plane was measured directly. From these measurements the experimental correction factors could be derived, which appeared to lie within the boundaries as theoretically predicted.\ud
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In general it may be concluded that the yield loci and their derived quantities as determined by a properly used Jenike shear tester are, as a rule, suitable for design purposes of e.g. silos. For comparison of results from different testing techniques, however, the deviations introduced by the loading mechanism cannot be neglected
Fluctuations in the level density of a Fermi gas
We present a theory that accurately describes the counting of excited states
of a noninteracting fermionic gas. At high excitation energies the results
reproduce Bethe's theory. At low energies oscillatory corrections to the
many--body density of states, related to shell effects, are obtained. The
fluctuations depend non-trivially on energy and particle number. Universality
and connections with Poisson statistics and random matrix theory are
established for regular and chaotic single--particle motion.Comment: 4 pages, 1 figur
Salivary gland-specific <i>P. berghei</i> reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes
Malaria is a life-threatening human infectious disease transmitted by mosquitoes. Levels of the salivary gland sporozoites (sgs), the only mosquito stage infectious to a mammalian host, represent an important cumulative index of <i>Plasmodium</i> development within a mosquito. However, current techniques of sgs quantification are laborious and imprecise. Here, transgenic <i>P. berghei</i> reporter lines that produce the green fluorescent protein fused to luciferase (GFP-LUC) specifically in sgs were generated, verified and characterised. Fluorescence microscopy confirmed the sgs stage specificity of expression of the reporter gene. The luciferase activity of the reporter lines was then exploited to establish a simple and fast biochemical assay to evaluate sgs loads in whole mosquitoes. Using this assay we successfully identified differences in sgs loads in mosquitoes silenced for genes that display opposing effects on <i>P. berghei</i> ookinete/oocyst development. It offers a new powerful tool to study infectivity of <i>P. berghei</i> to the mosquito, including analysis of vector-parasite interactions and evaluation of transmission-blocking vaccines
The Lyapunov exponent in the Sinai billiard in the small scatterer limit
We show that Lyapunov exponent for the Sinai billiard is with where
is the radius of the circular scatterer. We consider the disk-to-disk-map
of the standard configuration where the disks is centered inside a unit square.Comment: 15 pages LaTeX, 3 (useful) figures available from the autho
Challenges to Political Campaigns in the Media: Commercialization, Framing, and Personalization
Due to an increasing interdependence between mass communication and political processes, the role of media in political campaigns generated much debate.In this paper, we identify commercialization, framing and personalization as three key challenges to the way the media face political campaigns. We theoretically derive three hypotheses, one for each of those challenges. Based on data from expert interviews as well as from a content analysis, the validity of each hypothesis is surveyed.
The results do not confi rm an assumed lack of providing campaign relevant news in the media coverage as proposed by considering the media as purely commercially driven organizations. Further they demonstrate the use of different frames for the presentation of competing positions in a political debate. Finally, personalization appears as an important strategy of news selection, focusing on a small number of prominent actors
Riemann solvers and undercompressive shocks of convex FPU chains
We consider FPU-type atomic chains with general convex potentials. The naive
continuum limit in the hyperbolic space-time scaling is the p-system of mass
and momentum conservation. We systematically compare Riemann solutions to the
p-system with numerical solutions to discrete Riemann problems in FPU chains,
and argue that the latter can be described by modified p-system Riemann
solvers. We allow the flux to have a turning point, and observe a third type of
elementary wave (conservative shocks) in the atomistic simulations. These waves
are heteroclinic travelling waves and correspond to non-classical,
undercompressive shocks of the p-system. We analyse such shocks for fluxes with
one or more turning points.
Depending on the convexity properties of the flux we propose FPU-Riemann
solvers. Our numerical simulations confirm that Lax-shocks are replaced by so
called dispersive shocks. For convex-concave flux we provide numerical evidence
that convex FPU chains follow the p-system in generating conservative shocks
that are supersonic. For concave-convex flux, however, the conservative shocks
of the p-system are subsonic and do not appear in FPU-Riemann solutions
Level density of a Fermi gas: average growth and fluctuations
We compute the level density of a two--component Fermi gas as a function of
the number of particles, angular momentum and excitation energy. The result
includes smooth low--energy corrections to the leading Bethe term (connected to
a generalization of the partition problem and Hardy--Ramanujan formula) plus
oscillatory corrections that describe shell effects. When applied to nuclear
level densities, the theory provides a unified formulation valid from
low--lying states up to levels entering the continuum. The comparison with
experimental data from neutron resonances gives excellent results.Comment: 4 pages, 1 figur
Electronic Spectroscopy of He@C60+ for Astrochemical Consideration
The electronic spectrum of the endohedral fullerene He@C+60 observed by messenger spectroscopy in a cryogenic ion trap is presented. The role played by the messanger tag in the adopted experimental method is evaluated by recording spectra of He@C+60 − Hen with n = 1−4. The results indicate a linear shift of ∼ 0.7 Å in the wavelengths allowing accurate gas phase values to be reported. The presence of the helium inside the cage shifts the absorption bands by 2−3 Å toward shorter wavelengths compared to C+60. The magnitude of this displacement will enable searches for the spectral signatures of this fullerene analogue in interstellar environments by absorption spectroscopy. The implications for potential astronomical detection are discussed
Automated glycan assembly of <sup>19</sup>F labelled glycan probes enables high‐throughput NMR studies of protein‐glycan interactions
Protein‐glycan interactions mediate important biological processes, including pathogen host invasion and cellular communication. Major challenges to monitoring these low affinity interactions are the required high sensitivity of a biophysical assay and to cover a breath of synthetic well‐defined structures. Here, we showcase an expedite approach that integrates automated glycan assembly (AGA) of 19 F labelled probes and high‐throughput NMR methods, enabling the study of protein‐glycan interactions. Synthetic Lewis type 2 antigens were screened against seven glycan binding proteins (GBPs), including DC‐SIGN and BambL, respectively involved in HIV‐1 and lung infections in immunocompromised patients, confirming the preference for fucosylated glycans (Le x , H type 2, Le y ). Previously unknown glycan‐lectin weak interactions were detected, and thermodynamic data were obtained. Enzymatic reactions were monitored in real‐time, delivering kinetic parameters. These results demonstrate the utility of AGA combined with 19 F NMR for the discovery and characterization of glycan‐protein interactions, opening up new perspectives for 19 F labelled complex glycans
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